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biological models
A Whole-genome Model of DNA Replication in Human Cells
Dr. Francisco Berkemeier, University of Cambridge
May 28, 16:00
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17:00
B5 L5 R5209
genome
biological models
DNA replication is a fundamental cellular process and its precise regulation is crucial for maintaining genomic integrity. Inspired by the mathematical parallelism between DNA replication and the nucleation problem in one-dimensional crystal growth kinetics, we introduce a model that maps whole-genome replication dynamics based on the firing rate profiles of replication origins and fork movement.
